BMI and low vitamin D are causal factors for multiple sclerosis
نویسندگان
چکیده
منابع مشابه
vitamin d and multiple sclerosis.
multiple sclerosis (ms) is a chronic demyelinating disease and also is one of the most common disabling neurological disorders in young and middle-aged adults. the main pathogenesis of ms has long been thought to be an immune mediated disorder of the central nervous system. the function of the immune system is under the influence of vitamin d which as a modulator of immune response could play a...
متن کاملVitamin D and multiple sclerosis
Multiple sclerosis (MS) is a chronic demyelinating disease and also is one of the most common disabling neurological disorders in young and middle-aged adults. The main pathogenesis of MS has long been thought to be an immune mediated disorder of the central nervous system. The function of the immune system is under the influence of vitamin D which as a modulator of immune response could play a...
متن کاملVitamin D and multiple sclerosis.
The hypothesis that adequate vitamin D nutrition can contribute to the prevention of multiple sclerosis (MS) was originally proposed to explain the geographical distribution of MS, but only recently has the relation between various measures of vitamin D (eg, sun exposure, dietary sources, and serum concentrations of 25-hydroxyvitamin D) and risk of developing MS been rigorously investigated. Ov...
متن کاملMultiple sclerosis and vitamin D
Andrew J. Solomon, MD WHAT IS VITAMIN D AND WHY IS IT IMPORTANT IN MS? Vitamin D is a vitamin that acts like a hormone in the human body. We get vitamin D from sunlight, food, or dietary supplements. The study by Stein et al.1 examines the relationship of vitamin D and MS. In addition, a recent Patient Page in Neurology focused on the actions of vitamin D and vitamin D deficiency.2 The best lev...
متن کاملMendelian randomization shows a causal effect of low vitamin D on multiple sclerosis risk
OBJECTIVE We sought to estimate the causal effect of low serum 25(OH)D on multiple sclerosis (MS) susceptibility that is not confounded by environmental or lifestyle factors or subject to reverse causality. METHODS We conducted mendelian randomization (MR) analyses using an instrumental variable (IV) comprising 3 single nucleotide polymorphisms found to be associated with serum 25(OH)D levels...
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ژورنال
عنوان ژورنال: Neurology - Neuroimmunology Neuroinflammation
سال: 2020
ISSN: 2332-7812
DOI: 10.1212/nxi.0000000000000662